thymuskin best-practice

TYPE AND COURSE OF HAIR LOSS

Alopecia androgenetica

Women have an even course: hair thinning becomes readily apparent in the area of the part. Women usually do not become bald; in- stead, their hair noticeably thins.

Men initially develop a typical clear area in the forehead region with advancing bald corners, which may advance to becoming complete- ly bald in a share of affected persons.

hair loss prevention

Alopecia diffusa

Diffuse hair loss refers to the premature transition of hair from the growth phase (anagen phase) to the falling-out phase (telogen phase).

In persistent severe hair loss, the entire scalp hair thins and gradu- ally disappears as baldness progresses.

hair loss prevention

Alopecia areata

In the further course, delimited bald areas form, and may spread in spots over the entire head.
Some cases involve loss of all scalp hair (alopecia totalis) or body hair (alopecia sive universalis).

Thymuskin hair regeneration

Alopecia medicamentosa

Cytostatics administered during chemotherapy result in (usually reversible) loss of scalp hair depending on utilised active substanc- es and the dosage and duration of use.

In most cases, hair drops out completely about 3-5 weeks after the first chemotherapy. In milder courses, hair loss remains moderate in the ideal case.

Thymuskin

Own hair transplantation

Advancing androgenetic alopecia with subsequent hair transplantation and filling up thinned areas.

Mainly used by men.

Thymuskin

CAUSE

TEST RESULT

BEFORE / AFTER

» Genetic causes
» Hair roots react sensitively to DHT (dihydrotestosterone)
» Main cause of hair loss in men
» Hormonal changes are often triggers in women

» Reduces hair loss in an average of 96% of patients 1
» Improves seborrhea in at least 89% of patients1
» Removes itching in 74% of women

hair loss prevention

» Thyroid dysfunction
» Hormonal imbalances
» Iron deficiency
» Deficient diet (crash diet)
» Stress, burnout, emotional stress
» Medications

» Reduces hair loss in an average of 99% of patients1
» Improves seborrhea in at least 93% of women and 76% of men1
» Removes itching in 80% of women and 51% of men1

hair loss prevention

» Autoimmune process: The body‘s defense system acts against its own tissues or hair follicles
» Inflammatory hair loss disorder
» Alopecia areata is partly due to genetic causes.
» Hypersensitivity and emotional stress are assumed as other possible causes

» Reduction of daily number of lost hairs by 96%2
» New hair growth in 65%3 - 86%2 of patients
» Complete remission in 40% of patients3

hair regeneration process

» Cytostatics cause loss of scalp hair. This effect is due to the inhibitory effects of cytostatics on rapidly growing and frequently dividing cells
» Sub-form of diffuse hair loss, usually reversible
» The psychological effect is often still underestimated

» Thymuskin prevents hair loss or total reversible alopecia during cytostatic therapy three times more often com- pared to placebo6 or control group5
» In „mild“ cytostatic therapy, Thymus- kin preserves hair status in up to 94% of patients5
» Positive effects clearer in breast or colon cancer than in oesophageal or stomach cancer4

hair regeneration process

» An own hair transplant is usually done in the advanced stage of androgenetic alopecia

» Initial observations of use show rapid and healthy growth of transplanted follicular units

hair loss prevention

PRODUCT RECOMMENDATION

APPLICATION (symptom related)

» THYMUSKIN CLASSIC Shampoo & Serum for universal use against hair loss
» THYMUSKIN MED Shampoo & Serum Gel for severe hair loss, visible thinning and sensitive scalp and hair

Thymu skincare

» Use for at least 6 months. Initial successes usually become visible after about 12 weeks
» Androgenetically related hair loss is not a disease and cannot be cured. Therefore there may be renewed hair loss after terminating use
» In milder cases, long-term use of Thymuskin Shampoo is sufficient for follow-up treatment. If hair loss increases again, the combination of Thymuskin Shampoo and Serum should be used long-term

» THYMUSKIN MED Shampoo & Serum Gel against severe hair loss
» THYMUSKIN CLASSIC Shampoo & Serum for universal use against hair loss is also suitable in mild cases

Thymu skincare

» Use for approx. 6 months, depending on specific form and progression

» THYMUSKIN MED Shampoo & Serum Gel against severe hair loss and bald spots
» THYMUSKIN CLASSIC Shampoo & Serum for universal use against hair loss is also suitable in mild cases

Thymu skincare

» Use for at least 6 months, and for 12-24 months in case of baldness
» Bald areas should also be cleaned and prepared with Thymuskin Shampoo before using Thymuskin Serum

» THYMUSKIN FORTE Shampoo & Serum Gel against severe hair loss and for especially stressed scalp and hair
» For baldness or few remaining hairs, we recommend THYMUSKIN CLASSIC Shampoo in combination with THYMUSKIN FORTE Serum Gel
» THYMUSKIN CLASSIC Shampoo & Serum for universal use against hair loss is suitable in mild cases and preventively

Thymu skincare

» Ideally start using preventively four weeks before starting chemo- therapy. You can also start using it at any time during or after therapy
» Use until hair has regrown evenly and in its natural structure
» Bald areas should also be cleaned and prepared with Thymuskin Shampoo before using Thymuskin Serum

» THYMUSKIN MED Shampoo & Serum Gel for sensitive scalp and hair improves growth of transplanted hair follicles and lastingly supports hair growth

Thymu skincare

» After own hair transplants, you can wash the head with the pH-friendly Thymuskin Med Shampoo (silicone-free, paraben-free) for 1-2 days after the intervention
» After scabs heal (approx. 10-14 days), use for 3-6 months

APPLICATION (general)

» Wash hair with Thymuskin Shampoo, then apply Thymuskin Serum to scalp and massage into skin
» Adjust shampoo to washing rhythm, but at least 2-3x weekly

» Apply serum to scalp daily. Hair should be towel dried or dry beforehand
» Thymuskin is suitable for long-term use

Note
When starting to use Thymuskin, activation of hair follicles may result in slightly increased hair loss. In order to minimise this possible effect, you can start using only Thymuskin Shampoo in the first week, then add the use of Thymuskin Serum from the second week on every two days, and increase weekly to daily use in the fourth week. When the hair status has improved, fol- low this process in reverse order to complete the therapy.

Thymuskin hair loss prevention

THYMUSKIN MODE OF ACTION

» Thymuskin activates and nourishes hair follicles
» Thymuskin activates lymphocyte division
» Thymuskin increases cell vitality of keratinocytes
» The thymus peptide active substance GKL-02 acts as a direct modulator of hair growth
» The thymus peptide active substance GKL-02 inhibits various enzymes which play a decisive role in the development of hair loss (5α reductase, tryptase, trypsin and mast cells involved in hair loss)
» Hair loss in bald areas can often be reactivated up to three years after the hair loss occurred by using Thymuskin. Hair status is strengthened and the growth phase lengthens
» Thymuskin accelerates the regeneration process
» Thymuskin has anti-inflammatory properties and therefore positively affects all inflammatory forms of alopecia

effect of thymuskin on hair

1. Barbareschi M. et al.: Multizentrische Studie über die Wirksamkeit eines Serums und eines Shampoos zur lokalen Anwendung, die naturidentische Thymus-Peptide enthalten, zur
Anwendung bei androgenetischem Haarausfall und chronisch teleogenem Effluvium bei Frauen und Männern. Veröffentlicht 2013 im Journal of Plastic Dermatology (Ausgabe 9, 2013
· ISSN 2035-0686)

2. Mössler K.: Thymu-Skin: Neuer Therapieansatz bei der Behandlung der Alopecia androgenetica und der Alopecia areata. Der Deutsche Dermatologe 39, Heft 7 (1991)

3. Mössler K., Hagedorn M.: Lokaltherapie mit Thymusextrakt bei Alopecia areata totalis sive universalis. Sonderdruck aus »Der Deutsche Dermatologe« 11/1993, S. 1175-1182

4. Köhler C. O.: Unterschiedliche Erhaltung des Kopfhaares bei Chemotherapie mit verschiedenen Therapeutika. Interner Bericht aus dem Deutschen Krebsforschungszentrum, Heidel- berg, Abteilung Medizinische und Biologische Informatik.

5. Denck H., Wallner M.: Abschlußbericht über den 2. Teil Wien der Thymuskin-Haarstudie. Ludwig Boltzmann Institut für klinische Onkologie im Krankenhaus der Stadt Wien-Lainz.
29.5.1989

6. Lüpke N.-P.: Zusammenfassender Bericht zur adjuvanten lokalen Anwendung von Thymu-Skin-Präparationen bei Patienten unter zytostatischer Chemotherapie. Sonderdruck aus: Deutsche Zeitschrift für Onkologie 1/90

Clinical studies available on request for professionals: info@thymuskin.de